If you cannot find your prescription, call your doctor before running out entirely. Stopping stimulant medication abruptly can cause fatigue, irritability, difficulty concentrating, and other withdrawal-like effects. Your doctor may be able to help you find a pharmacy with stock, or discuss a short-term alternative.
The short version: The FDA officially declared a shortage of amphetamine mixed salts — sold under the brand name Adderall and many generic versions — in October 2022. The shortage was caused by a combination of rising demand, manufacturing delays, and federally imposed limits on how much of the drug can be produced each year. Despite efforts to address it, the shortage remains active on the FDA's drug shortages database. Millions of patients have been affected, and the disruption has caused real harm for many families.
What the Shortage Is and How Long It Has Been Going On
Adderall is a brand-name version of amphetamine mixed salts, a stimulant medication used to treat attention-deficit/hyperactivity disorder (ADHD) and, in some cases, narcolepsy. The generic version — amphetamine mixed salts — is one of the most widely prescribed medications in the United States. According to the American Psychiatric Association, ADHD affects approximately 8 to 9 percent of children and about 4 to 5 percent of adults.
The FDA declared an official shortage in October 2022. At that point, the agency said the primary manufacturer — Teva Pharmaceuticals — was experiencing production delays that were limiting supply. But as more time passed, it became clear this was not just one manufacturer's problem. Multiple generic makers were struggling to keep up with demand, and the problem fed on itself: when some pharmacies ran out, patients rushed to others, accelerating the depletion of remaining stock.
What made this shortage unusual is how long it has lasted. Most drug shortages resolve within months. This one has persisted for years, making it one of the longest-running prescription drug shortages in recent FDA history.
Why It Happened
The Adderall shortage has two main causes, and understanding both matters because they point to different parts of the system that failed patients.
Demand surged while supply stayed flat. During the COVID-19 pandemic, telehealth expanded dramatically and made it easier for people to get evaluated and diagnosed with ADHD. The number of new Adderall prescriptions increased significantly between 2020 and 2022. Manufacturers, however, did not have the ability to simply ramp up production in response.
Federal quotas limit how much can be made. Amphetamines are a Schedule II controlled substance under federal law, which means the Drug Enforcement Administration (DEA) sets a maximum amount that manufacturers are allowed to produce each year. These limits are called production quotas, and they are designed to prevent abuse. But in this case, the quotas could not keep pace with a legitimate, documented increase in demand — leaving pharmacies short and patients scrambling.
Who Is Most Affected
The shortage has touched millions of people, but some groups have felt it more sharply than others:
- Children with ADHD who depend on medication to stay focused at school. When a child misses days of medication, it can affect their grades, their behavior in class, and their relationships with teachers and classmates.
- Adults with ADHD who rely on the medication to function at work. ADHD without medication can make it very difficult to meet deadlines, stay organized, or complete complex tasks consistently.
- People with severe ADHD for whom stimulant medications work significantly better than the alternatives. Not every patient responds equally to substitute drugs, and some cannot tolerate them at all.
- Patients in areas with fewer pharmacy options, particularly in rural communities, where calling around to find a pharmacy with stock can mean driving hours away.
Reports of patients crying in pharmacies, missing work, falling behind in school, and experiencing mental health crises after going days or weeks without medication have been documented widely in the media since the shortage began.
What to Do If You Cannot Find Your Prescription
The shortage is ongoing, but there are steps that can help:
- Call pharmacies before going in person and ask specifically about your dose and formulation. Availability varies significantly by location, even within the same pharmacy chain.
- Ask your doctor to check their prescribing system for pharmacies with confirmed stock. Some electronic prescribing platforms now show real-time inventory.
- Ask about a different formulation. Adderall XR (extended-release) and Adderall IR (immediate-release) are made differently and may have different availability. The same goes for brand versus generic versions.
- Ask about alternatives. Vyvanse (lisdexamfetamine), Ritalin (methylphenidate), and Strattera (atomoxetine) are among the alternatives your doctor might consider. They do not work the same way for everyone, but they may be available when amphetamines are not.
- Try mail-order or specialty pharmacies. They sometimes have different supply chains than retail locations.
- Do not go without medication if you can avoid it — call your doctor and explain the situation before you run out entirely.
When This Becomes More Than an Inconvenience
For many patients, the shortage has been a serious disruption. But for some, it has caused real, lasting harm — and that is a different situation entirely.
Stopping stimulant medications abruptly can cause a range of difficult symptoms: intense fatigue, depression, increased anxiety, inability to concentrate, mood swings, and sleep problems. For someone with severe ADHD who has been stable on medication, losing access suddenly can be genuinely destabilizing.
There are patients who have lost jobs because they could not maintain their performance without medication. Students who failed courses or semesters. People who went through mental health crises. People who had accidents because their ability to focus was severely compromised.
If you or a family member experienced serious consequences — job loss, academic failure, a mental health crisis, a physical injury — because you were unable to get the ADHD medication you needed during this shortage, it may be worth asking whether there is legal accountability for what happened to you. A lawyer who handles cases like this can listen to your story and tell you honestly whether your situation might qualify.
Sources
- U.S. Food and Drug Administration. "Drug Shortages: Amphetamine Mixed Salts." accessdata.fda.gov/scripts/drugshortages/default.cfm. Accessed June 2026.
- U.S. Drug Enforcement Administration. "Controlled Substance Schedules." DEA Office of Diversion Control. dea.gov. Accessed June 2026.
- American Psychiatric Association. "What Is ADHD?" psychiatry.org. Accessed June 2026.
- CHADD (Children and Adults with ADHD). "ADHD Medication Shortage Resource Center." chadd.org. Accessed June 2026.
- The Washington Post. "Adderall shortage leaves ADHD patients struggling to find medication." October 2022.
- U.S. Food and Drug Administration. "FDA Statement on Adderall Shortage." October 2022. fda.gov.
- Goodman, D.W. "ADHD in Adults: Update for Clinicians on Diagnosis and Assessment." Primary Psychiatry, 2009. (Background on ADHD prevalence.)