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Open Pharma Toxic Exposure

Women Who Used Depo-Provera Birth Control and Later Developed a Brain Tumor May Be Owed Money After a 5.6x Risk Finding

A major 2024 study found that women who used Depo-Provera for a year or more were more than five times as likely to develop a meningioma brain tumor. Lawsuits against Pfizer are now open and accepting cases.

By Lawsuit Loop Staff · Published Apr 23, 2026 · 6 min read · Updated weekly
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The short version: Depo-Provera is a birth control shot that millions of women have used. A 2024 study published in the British Medical Journal found that women who used it for a year or more were 5.6 times more likely to develop a meningioma — a type of brain tumor. If you used Depo-Provera and were later diagnosed with a meningioma, you may be owed money. Filing is open and there is no cost to check.

This page explains what the lawsuit is about, who may qualify, and what happens if you file. If you'd rather go straight to a case check, the form is at the bottom of this page.

What the Depo-Provera Lawsuit Is About

Depo-Provera is an injectable form of birth control containing medroxyprogesterone acetate, a synthetic hormone. It is made by Pfizer and has been used by millions of women in the United States since it was approved by the FDA in 1992. The shot is given every three months.

The lawsuits allege that Pfizer knew — or should have known — that long-term use of Depo-Provera significantly raises the risk of developing a meningioma, a tumor that grows on the membranes surrounding the brain. In February 2024, a large study published in the British Medical Journal found that women who used progestin-based hormonal contraceptives like Depo-Provera for a year or more had a 5.6 times higher risk of developing an intracranial meningioma compared to women who did not use the drug. (Passildas-Jahanmohan et al., BMJ, 2024.)

The lawsuits allege Pfizer failed to adequately warn patients and doctors about this risk. Cases are currently being filed in federal court, and an MDL (Multi-District Litigation) consolidation is underway. All defendants deny the allegations.

Who May Qualify

You may have a case if all three of the following apply:

  • You received Depo-Provera injections (medroxyprogesterone acetate) for birth control.
  • You used Depo-Provera for one year or more, either continuously or cumulatively.
  • You were later diagnosed with a meningioma — a brain or spinal cord tumor affecting the meninges.

You do not need to still be using Depo-Provera. Many women who stopped years ago and were later diagnosed with a meningioma may still qualify.

Think You May Qualify?

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Tell us how long you used Depo-Provera and when you were diagnosed. A real person will review your info and reach out within one week if you may have a case.

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What Is a Meningioma?

A meningioma is a tumor that forms on the meninges — the layers of tissue that surround and protect the brain and spinal cord. Most meningiomas grow slowly and are not cancerous in the traditional sense, but they can grow large enough to press on the brain and cause serious, life-altering symptoms.

Common symptoms include:

  • Persistent or worsening headaches
  • Vision problems, including blurry or double vision
  • Hearing loss or ringing in the ears
  • Memory problems or confusion
  • Seizures
  • Weakness or numbness in the arms or legs

Treatment often requires brain surgery and/or radiation therapy. Recovery can take months or years, and some patients experience lasting effects even after treatment.

What Could This Mean for You?

We will not quote you a number. No global settlement has been reached in this litigation as of this writing, and there is no verified basis to project what any individual case may be worth. Anyone offering you a specific figure at this stage is guessing — and we will not do that.

What any case may ultimately be worth depends on factors including the severity of your diagnosis, treatment costs, lost income, and how the litigation resolves — all of which are unique to your situation.

What we can say: the case check is free, you owe nothing unless you win, and the only way to know if you may have a case is to submit your information for review.

Filing Deadline

Every state sets its own deadline for filing a personal injury lawsuit. In many states, that window is two to three years from when you first connected your diagnosis to the drug. Once the deadline passes, you cannot file — even if your case would have been strong.

Checking is free and takes about two minutes. Do not wait.

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How the Process Works

Step 1 — The Free Case Check

Fill out the form on this page. It takes about two minutes. Our intake team reviews it. If it looks like you may qualify, someone reaches out within one week.

Step 2 — A Screening Conversation

A team member contacts you to learn more: how long you used Depo-Provera, when you were diagnosed, and what treatment you've needed. No cost. No pressure.

Step 3 — Signing Up

If you move forward, you sign a simple agreement. You owe nothing unless your case wins or settles. If you win, a percentage goes to the law firm; the rest is yours.

Step 4 — Your Case Joins Others

Your case joins the broader Depo-Provera litigation. The law firm handles the legal work. Most clients never go to court themselves. When cases resolve, payouts go out.

Common Questions

I stopped using Depo-Provera years ago. Can I still file?

Yes. Many women stopped using Depo-Provera before their meningioma was diagnosed. You may still qualify even if you have not had a Depo-Provera shot in years.

My meningioma was described as "benign." Does that matter?

Not necessarily. Even a non-cancerous meningioma can require surgery, cause lasting damage, and significantly impact your quality of life. These cases may still qualify.

Do I need my medical records to get started?

Helpful, but not required to start. Your pharmacy and medical records can confirm your Depo-Provera use and diagnosis. The law firm can help you obtain those if needed.

Does this apply in all states?

Yes. Women from all 50 states are eligible to file. Filing deadlines vary by state, which is why acting sooner matters.

Does it cost anything?

No. The case check is free. If you sign up and your case does not recover money, you owe nothing.

Sources

  • Passildas-Jahanmohan, J. et al., "Use of progestins and risk of intracranial meningioma," The BMJ, 2024. bmj.com
  • U.S. Food & Drug Administration, Depo-Provera product labeling and safety communications. fda.gov
  • National Institutes of Health, MedlinePlus: Meningioma overview. medlineplus.gov
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